6h8t | pdb_00006h8t

Crystal structure of Papain modify by achiral Ru(II)complex

spinqualitylabelsall models 6h8t, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6h8t is a 2 chain structure with sequence from Carica papaya. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.1Å Ligands: ACT, CL, NA, OMX, SO4, TXY, YXX, YXZ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PAPA1_CARPA Publication Abstract from PubMed The X-ray structure of an aerated achiral Ru-papain conjugate has revealed the hydroxylation of two tyrosine residues found near the ruthenium ion. The most likely mechanism involves a ruthenium-bound superoxide as the reactive species responsible for the first hydroxylation and the resulting high valent Ru(iv)[double bond, length as m-dash]O species for the second one. Crystallographic evidence for unexpected selective tyrosine hydroxylations in an aerated achiral Ru-papain conjugate.,Cherrier MV, Amara P, Talbi B, Salmain M, Fontecilla-Camps JC Metallomics. 2018 Sep 3. doi: 10.1039/c8mt00160j. PMID:30175357 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Papain

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