Structural highlights
Function
DNLJ_DEIRA DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588][1]
References
- ↑ Blasius M, Buob R, Shevelev IV, Hubscher U. Enzymes involved in DNA ligation and end-healing in the radioresistant bacterium Deinococcus radiodurans. BMC Mol Biol. 2007 Aug 16;8:69. PMID:17705817 doi:10.1186/1471-2199-8-69