Nucleoporin 3D structures

3D Structures of Nucleoporin

Updated on 30-March-2026

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• NUP2
  • 3n7c – NUP2 RANBD – Ashbya gossypii
    
  • 2c1t – yNUP2 NTD +importrin alpha subunit - yeast
    
• NUP35
  • 8ozb – hNUP35 + nanobody - human
    
  • 1wwh – mNUP35 MPPN domain - mouse
    
• NUP37
  • 4fhl – fyNUP37 – fission yeast
    
  • 4fhm, 4fhn, 4gq2 - fyNUP37 + NUP120
    
• NUP43
  • 4i79 – hNUP43 + polypeptide
    
• NUP50
  • 2ec1 – hNUP50 RANBD 337-468
    
  • 7mo0 - hNUP50 RANBD + RAN
    
  • 3tj3 - hNUP50 NTD+importin
    
  • 2c1m – mNUP50 NTD +importin
    
• NUP53
  • 3p3d - NUP53 RRM domain - Pischia guillermondii
    
  • 4lir – hNUP53 residues 151-266
    
  • 5uaz – yNUP53
    
  • 5hb7, 5hb8 – CtNUP53 - Chaetomium thermophilum
    
  • 5hb3 – CtNUP53 + NUP NIC96
    
• NUP54
  • 4jo7, 4jo9 – hNUP54 + hNUP58/45
    
  • 3t97 – rNUP54 + NUP62 - rat
    
  • 4j3h – rNUP54 (mutant)
    
  • 3t98 – rNUP54 + rNUP58/45
    
  • 5c3l – fNUP54 coiled coil + NUP58 coiled coil + NUP62 coiled coil + nanobody - frog
    
  • 5c2u – fNUP54 ferredoxin-like domain + nanobody
    
• NUP57
  • 5cwt – CtNUP57 residues 265-317
    
  • 5cws – CtNUP57 residues 74-319 + NUP49 + NIC96 + antibody
    
• NUP58
  • 4jq5 – hNUP58/45
    
  • 2osz – rNUP58/45
    
• NUP62
  • 5h1x – rNUP62 coiled-coil domain
    
• NUP82
  • 3pbp – yNUP82 NTD + NUP116 CTD + NUP159 CTD
    
  • 3tkn - yNUP82 NTD + NUP98 + NUP159 CTD
    
  • 5cww – CtNUP82 + CtNUP145 CTD peptide + Ct159 CTD peptide
    
• NUP84
  • 3jro, 3iko – yNUP84+NUP145+protein Sec13
    
  • 4xmm - yNUP84+NUP85+NUP120+NUP145+protein Seh1 + antibody
    
  • 8tie - yNUP84+NUP85+NUP120+NUP133+NUP145+NUP Seh1 + SEC13 – Cryo EM
    
  • 4xmn - yNUP84+NUP85+NUP120+NUP145 + antibody
    
  • 6x02, 6x03 – yNUP84 + NUP133 + nanobody
    
• NUP85
  • 3ewe, 3f3f, 3f3g, 3f3p – yNUP85+Seh1
    
  • 6x08 - yNUP85+Seh1 + nanobody
    
• NUP88
  • 7mni – hNUP88 NTD 1-493 + NUP98 715-863
    
• NUP93
  • 7mw0 – hNUP93 174-819
    
  • 7mw1 – hNUP93 174-819 + NUP53 84-150
    
• NUP96
  • 7nqa – fNUP96 + nanobody
    
• NUP98
  • 3mmy – hNUP98 fragment+mRNA export factor
    
  • 1ko6, 2q5x, 2q5y – hNUP98 CTD
    
  • 7q65, 7q66, 7q67 – hNUP98 85-124 – Cryo EM
    
  • 7now – fNUP98 + nanobody
    
  • 7nq6 – fNUP98 CTD
    
• NUP100
  • 3nf5 – NUP100 CTD – Candida glabrata
    
• NUP107
  • 3cqc, 3cqg, 3i4r – hNUP107+NUP133
    
• NUP116
  • 2aiv – yNUP116 CTD - NMR
    
• NUP120
  • 3f7f, 3h7n, 3hxr – yNUP120
    
  • 6x06 – yNUP120 + nanobody
    
• NUP133
  • 1xks, 4q9t – hNUP133 NTD
    
  • 3kfo – yNUP133 CTD
    
  • 6x04, 6x05 – yNUP133 + nanobody
    
• NUP145
  • 3bg0, 3bg1 – hNUP145+Sec13-related protein
    
  • 3kep, 3kes – yNUP145 autoproteolytic domain
    
  • 3jrp - yNUP145+protein Sec13
    
  • 5hb5 – CtNUP145
    
  • 5hb6 – CtNUP145 (mutant)
    
• NUP152
  • 5tvz – yNUP152 Ig-like repeats - NMR
    
• NUP153
  • 7mo1 – hNUP153 zinc finger 1 648-687 +RAN
    
  • 3gj3, 3gj4, 3gj5, 3gj6, 3gj7, 3gj8, 3ch5, 7mo3, 7mo4 – hNUP153 zinc finger 2 723-750 +RAN
    
  • 7mo5 – hNUP153 zinc finger 4 838-874 +RAN
    
  • 2ebq, 2ebr, 2ebv, 2gqe - hNUP153 RANBD – NMR
    
  • 2k0c – rNUP153 RANBD – NMR
    
  • 7mo2 - rNUP153 zinc finger 2 +RAN
    
• NUP155
  • 7r1y – hNUP155 NTD 19-981 – Cryo EM
    
  • 7eyf – hNUP155 CTD 864-1337 – Cryo EM
    
  • 7eye – NUP155 19-863 – RVSV – Cryo EM
    
  • 7eyq – NUP155 19-1069 – RVSV – Cryo EM
    
• NUP157
  • 4mhc – hNUP157 NTD
    
• NUP159
  • 1xip – yNUP159 NTD
    
  • 3rrm – yNUP159 residues 2-387 + NUP Gle1 + IP6 + ADP
    
• NUP170
  • 3i5p, 3i5q – yNUP170
    
  • 5hb1 – CtNUP170
    
  • 5haz – CtNUP170 CTD
    
  • 5hay – CtNUP170 CTD (mutant)
    
  • 5hb0 – CtNUP170 (mutant) + CtNUP145 peptide
    
  • 5hax – CtNUP170 NTD + CtNUP53 peptide
    
• NUP188
  • 7wo9 – yNUP188 – Cryo EM
    
  • 5cwu – CtNUP188 tail domain
    
  • 7mvw – CtNUP188 NTD 1-1134
    
  • 7mvx – CtNUP188 + Nic96 peptide
    
  • 7mvy – CtNUP188 + Nic96 peptide – Cryo EM
    
  • 7mvz – CtNUP188 + NUP145 640-732 + Nic96 peptide – Cryo EM
    
• NUP192
  • 4ifq – yNUP192
    
  • 5hb4 – CtNUP192
    
  • 7mvu – CtNUP192 1-1756 + Nic96 – Cryo EM
    
  • 7mvt – CtNUP192 185-1756 + Nic96
    
  • 5cwv – CtNUP192 tail domain
    
• NUP214
  • 3fhc, 3fmo, 3fmp – hNUP214+dead-box helicase
    
  • 2oit – hNUP214 NTD
    
• NUP358
  • 1z5s – hNUP358 IR1 domain+ubiquitin-conjugating enzyme+SMT3C+RAN CTD
    
  • 1xke - hNUP358 RANBD - NMR
    
  • 9b62 - hNUP358 in nucleoporin exportin complex – Cryo EM
    
• NUP1P
  • 5owu – NUP1P+Kap95 complex
    
• NUP2P
  • 1un0 – yNUP2P NTD+imporrin α subunit
    
• NUP-NSP1
  • 1o6o – yNUP-NSP1 residues 497-608+importrin β subunit
    
• NUP-CDC31
  • 2doq, 2gv5 – yNUP-CDC31+SFI1P
    
  • 3fwb, 3fwc - yNUP-CDC31+SAC3
    
• NUP Gle1
  • 3peu, 3pev, 3rrn– yNUP-Gle1 + ATP-dependent RNA helicase Dbp5 (mutant) +IP6
    
  • 6b4e – yNUP-Gle1 + NUP42
    
  • 6b4g, 6b4h – CtNUP-Gle1 + NUP Amo1
    
• NUP-Nic96
  • 2qx5, 2rfo – yNic96
    
  • 6x07 – yNic96 + nanobody
    
  • 5hb2 – CtNic96
    
  • 1gyb – NUP+yNTF2
    
• NUP Pom34
  • 8t9l – yNUP-Pom34 + yNUP-Pom152 – Cryo EM
    
• NUP-SEH1
  • 7uhy, 9lwf, 9oti – hNUP in GATOR2 complex – Cryo EM
    
  • 9lvj – hNUP in GATOR2 complex + sestrin-2 – Cryo EM
    
  • 9lvk – hNUP in GATOR2 complex + CASTOR1– Cryo EM
    
  • 8adl – yNUP in SEA complex – Cryo EM
    
  • 9h5k – yNUP in SEAC-EGOC complex – Cryo EM
    
• Nuclear pore complex
  • 5ijn, 5ijo, 7peq, 7per, 7r5j, 7r5k, 8tj5 – hNUP in pore complex – Cryo EM
    
  • 5a9q – hNUP96 + NUP133 + NUP160 + NUP43 + NUP37 + NUP85 + NUP155 + NUP107 + Sec13 + Seh1 – Cryo EM
    
  • 6lk8, 7fik, 7tdz, 7vop, 7wb4, 7wkk – fNUP in ring complex – Cryo EM
    
  • 9sob – NUP in pore complex – Arabidopsis thaliana - Cryo EM
    
  • 7n84, 7n85, 7n9f, 7vci, 7woo, 7wot – yNUP in pore complex – Cryo EM
    
  • 9hcj – NUP in pore complex – Dictyostelium discoideum - Cryo EM
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel