9ori | pdb_00009ori

Crystal structure of clinically relevant H117Y mutant of AGR2

spinqualitylabelsall models 9ori, resolution 1.74Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9ori is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.74Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AGR2_HUMAN Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

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