9svz | pdb_00009svz

The structure of S. aureus alpha-hemolysin in complex with a bicyclic peptide inhibitor

spinqualitylabelsall models 9svz, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9svz is a 4 chain structure with sequence from Staphylococcus aureus and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.4Å Ligands: ACT, CL, EDO, GOL, MG, R06 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HLA_STAAU Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity.

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