Pyrrolysyl-tRNA synthetase 3D structures

Updated on 25-August-2026

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• Pyrrolysyl-tRNA synthetase
  • 6ezd, 6jp2 – CmPTS – Candidatus methanomethylophilius
    
  • 2e3c, 8ris – MmPTS catalytic domain 185-454 – Methanosarcina mazei
    
  • 2znj, 3dsq – DhPTS – Desulfitobacterium hafniense
    
  • 7r6o, 8ifj – PTS – Methanogenic archaon
    

Pyrrolysyl-tRNA synthetase binary complex

• • 8c49 – CmPTS + ANP
    
  • 2q7e, 3vqw – MmPTS catalytic domain + ANP
    
  • 4bw9, 4cs4, 5k1p, 5k1x – MmPTS catalytic domain (mutant) + ANP
    
  • 3vqx – MmPTS catalytic domain (mutant) + AMP
    
  • 4bwa – MmPTS catalytic domain (mutant) + norbornene
    
  • 4ch3, 4ch4, 4ch5, 4ch6 – MmPTS catalytic domain + Lys derivative
    
  • 5ud5 – MmPTS tRNA-binding domain 1-101 + tRNA
    
  • 5v6x – MmPTS tRNA-binding domain (mutant) + tRNA
    
  • 2zni – DhPTS + tRNA
    

Pyrrolysyl-tRNA synthetase ternary complex

• • 7u0r – CmPTS (mutant) + malonate derivative + ANP
    
  • 2zce, 2zim – MmPTS catalytic domain + pyrrolysine + ANP
    
  • 2q7h – MmPTS catalytic domain + pyrrolysine + POP
    
  • 2q7g – MmPTS catalytic domain + pyrrolysine + ATP
    
  • 6aaz, 6ab8, 6abk, 6abl – MmPTS catalytic domain (mutant) + Lys + ATP
    
  • 2zio, 3vqv – MmPTS catalytic domain + Lys-AMP + PNP
    
  • 2zin, 3vqy – MmPTS catalytic domain + Lys + ANP
    
  • 4q6g – MmPTS catalytic domain (mutant) + Lys + ADPNP
    
  • 6aac, 6aad, 6aan, 6aao, 6aaq, 6ab0, 6ab1, 6ab2, 6abm – MmPTS catalytic domain (mutant) + Lys + ATP
    
  • 6aap – MmPTS catalytic domain (mutant) + Cys + ATP
    
  • 3qtc – MmPTS catalytic domain + Tyr + ANP
    
  • 7rsm – MmPTS catalytic domain + Phe + ANP
    
  • 4tqd – MmPTS catalytic domain + Phe + ATP
    
  • 8ke1, 8ke2, 8ke3, 8ke4, 8ke5, 8ke6 – MmPTS catalytic domain (mutant) + Phe + ANP
    
  • 6ly7, 6lya – MmPTS catalytic domain (mutant) + Trp + ANP
    
  • 6ly3, 6ly6, 6lyb – MmPTS catalytic domain (mutant) + Ala + ANP
    
  • 4cs3 – MmPTS catalytic domain (mutant) + amino acid + AMP + POP
    
  • 4tqf – MmPTS catalytic domain + Ala + ATP
    
  • 4zib – MmPTS catalytic domain (mutant) + Ala + ATP
    
  • 8dqg, 8dqh, 8dqi – CmPTS + acridone + ANP
    
  • 8dqj – CmPTS + acridone + ATP
    

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Michal Harel