Structural highlights
Function
MGAT1_HUMAN Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.[1] [2]
References
- ↑ Kumar R, Yang J, Larsen RD, Stanley P. Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation. Proc Natl Acad Sci U S A. 1990 Dec;87(24):9948-52. doi: 10.1073/pnas.87.24.9948. PMID:1702225 doi:https://dx.doi.org/10.1073/pnas.87.24.9948
- ↑ Jaroentomeechai T, Kwon YH, Liu Y, Young O, Bhawal R, Wilson JD, Li M, Chapla DG, Moremen KW, Jewett MC, Mizrachi D, DeLisa MP. A universal glycoenzyme biosynthesis pipeline that enables efficient cell-free remodeling of glycans. Nat Commun. 2022 Oct 24;13(1):6325. doi: 10.1038/s41467-022-34029-7. PMID:36280670 doi:https://dx.doi.org/10.1038/s41467-022-34029-7
