31hx | pdb_000031hx

Mycobacterium tuberculosis transcription termination factor Rho in complex with an RNA substrate bound to the primary binding site and the ATP analogue ADP-BeF3

spinqualitylabelsall models 31hx, resolution 3.15Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 31hx is a 6 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.15Å Ligands: ADP, BEF, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function RHO_MYCTO Facilitates transcription termination from RNA polymerase (RNAP) by binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, translocation in a 5'-3' direction on the RNA (toward RNAP), and release of the RNA from the DNA template.[HAMAP-Rule:MF_01884] Plays a major role in reduction of R-loop formation across the genome; R-loops can be generated by annealing of untranslated (often antisense) RNA to upstream DNA.[HAMAP-Rule:MF_01884]

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