32cp | pdb_000032cp

Horse spleen Holoferritin 5.8 MGy variable temperature dose series, 100 K

spinqualitylabelsall models 32cp, resolution 2.33Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 32cp is a 1 chain structure with sequence from Equus caballus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.33Å Ligands: CD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function FRIL_HORSE Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). Publication Abstract from PubMed The behaviour of the unit-cell volume of crystals of the iron-storage molecule ferritin, both in the apo and the holo form, and of influenza A virus subtype N9 neuraminidase at 100 K and over a controlled cryo-temperature series was investigated. The purpose of this study was to separate out the effects of dose and temperature on the protein by assessing the changes in the unit-cell volume. Over the wide range of X-ray doses examined in this work, the irreversible effect of dose on the unit-cell volume could be distinguished from the reversible (below 160 K) temperature-induced effects. Specific structural damage effects were not reversible. Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.,Southworth-Davies RJ, Murray JW, Carmichael I, Rudino-Pinera E, Weik M, Garman EF Acta Crystallogr D Struct Biol. 2026 Oct 1. doi: 10.1107/S2059798326008612. PMID:42741972 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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