2flr | pdb_00002flr
Novel 5-Azaindole Factor VIIa Inhibitors
Overview
The discovery and development of 5-azaindole factor VIIa inhibitors will be described.
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
2FLR is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Novel 5-azaindole factor VIIa inhibitors., Riggs JR, Hu H, Kolesnikov A, Leahy EM, Wesson KE, Shrader WD, Vijaykumar D, Wahl TA, Tong Z, Sprengeler PA, Green MJ, Yu C, Katz BA, Sanford E, Nguyen M, Cabuslay R, Young WB, Bioorg Med Chem Lett. 2006 Jun 15;16(12):3197-200. Epub 2006 Apr 18. PMID:16621549 Page seeded by OCA on Sun May 4 04:02:35 2008
