2p8h | pdb_00002p8h

File:2p8h.gif

spinqualitylabelsall models 2p8h, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

Crystal structure of human beta secretase complexed with inhibitor

About this Structure

2P8H is a Single protein structure of sequence from Homo sapiens with MY9 as ligand. Active as Memapsin 2, with EC number 3.4.23.46 Full crystallographic information is available from OCA.

Reference

Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul 9;2(7):995-999. PMID:17458843

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