Sandbox 3

MHC Class I

spinqualitylabelsall models Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

Exploring the Structure

You can take a close look at the peptide in HLA-B*3508 in the PDB entry 2h6p. This is made up of a heavy chain and the immunoglobulin like domain, beta2m,

TCR

The TCR is made up of an alpha and beta chain. pMHC Surface seen by TCR

TCR_PMHC

Note the peptide in the binding groove