1ghv | pdb_00001ghv
From Proteopedia
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
About this Structure
1GHV is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site., Katz BA, Elrod K, Luong C, Rice MJ, Mackman RL, Sprengeler PA, Spencer J, Hataye J, Janc J, Link J, Litvak J, Rai R, Rice K, Sideris S, Verner E, Young W, J Mol Biol. 2001 Apr 13;307(5):1451-86. PMID:11292354
Page seeded by OCA on Tue Jul 1 05:18:31 2008
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Categories:
- Pages with broken file links
- Homo sapiens
- Protein complex
- Thrombin
- Elrod, K.
- Hatayte, J.
- Janc, J.
- Katz, B A.
- Link, J.
- Litvak, J.
- Luong, C.
- Mackman, R L.
- Rai, R.
- Rice, K.
- Rice, M.
- Sideris, S.
- Spencer, J.
- Sprengeler, P A.
- Verner, E.
- Young, W.
- Oxyanion hole water
- Shift of pka of his57
- Specificity
- Structure-based drug design
- Three-centered
- Trypsin
- Urokinase
- Very short hydrogen bond
- Zn+2-mediated inhibition