1gd6 | pdb_00001gd6
STRUCTURE OF THE BOMBYX MORI LYSOZYME
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Overview
Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme., BmLZ has considerable activity at low temperatures and low activation, energies compared with those of hen egg white lysozyme (HEWLZ), according, to measurements of the temperature dependencies of relative activity, (lytic and glycol chitin) and the estimation of activation energies using, the Arrhenius equation. Being so active at low temperatures and low, activation energies is characteristic of psychrophilic (cold-adapted), enzymes. The three-dimensional structure of BmLZ has been determined by, X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is, similar to that of c-type lysozymes. However, BmLZ shows some distinct, differences in the two exposed loops and the C-terminal region. A detailed, comparison of BmLZ and HEWLZ suggests structural rationalizations for the, differences in the catalytic efficiency, stability, and mode of activity, between these two lysozymes.
About this Structure
1GD6 is a Single protein structure of sequence from Bombyx mori. Active as Lysozyme, with EC number 3.2.1.17 Full crystallographic information is available from OCA.
Reference
Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures., Matsuura A, Yao M, Aizawa T, Koganesawa N, Masaki K, Miyazawa M, Demura M, Tanaka I, Kawano K, Nitta K, Biochemistry. 2002 Oct 8;41(40):12086-92. PMID:12356308
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