1jk3 | pdb_00001jk3

File:1jk3.png

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1jk3, resolution 1.09Å (default scene)
Ligands:	BAT, CA, ZN
Activity:	Macrophage elastase, with EC number 3.4.24.65
Structural annotation: Resources: CATH : 1Jk3A00 InterPro : Ipr006025, Ipr000585, Ipr001818, Ipr006026, Ipr002477 Pfam : PF00413 SCOP : d1jk3a_ UniProt : P39900
Functional annotation: Cellular component: proteinaceous extracellular matrix Biological process: metabolic process cell motility proteolysis Molecular function: peptidase activity zinc ion binding catalytic activity hydrolase activity calcium ion binding metallopeptidase activity metal ion binding macrophage elastase activity metalloendopeptidase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

About this Structure

1JK3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure., Lang R, Kocourek A, Braun M, Tschesche H, Huber R, Bode W, Maskos K, J Mol Biol. 2001 Sep 28;312(4):731-42. PMID:11575928

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