2uxx | pdb_00002uxx
HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT
Template:ABSTRACT PUBMED 17569509
About this Structure
2UXX is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine., Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H, Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509
Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase., Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H, Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027
Page seeded by OCA on Sun Jul 27 12:37:33 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Homo sapiens
- Protein complex
- Cole, P A.
- Culhane, J C.
- Machius, M.
- Yang, M.
- Yu, H.
- Alternative splicing
- Chromatin demethylation
- Chromatin regulator
- Coiled coil
- Corest
- Depression
- Fad
- Histone demethylase
- Host-virus interaction
- Lsd1
- Nuclear protein
- Nucleosome
- Oxidoreductase
- Oxidoreductase/repressor complex
- Phosphorylation
- Repressor
- Transcription
- Transcription regulation
- Tranylcypromine