1o4n | pdb_00001o4n

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File:1o4n.png

Template:STRUCTURE 1o4n

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH OXALIC ACID.

Template:ABSTRACT PUBMED 14613321

Disease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this Structure

1O4N is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors., Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E, J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321

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