2vnn | pdb_00002vnn
From Proteopedia
HUMAN BACE-1 IN COMPLEX WITH 7-ETHYL-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL)METHYL)AMINO) PROPYL)-1-METHYL-3,4-DIHYDRO-1H-(1,2,5)THIADIAZEPINO(3,4,5-HI)INDOLE-9-CARBOXAMIDE 2,2-DIOXIDE
About this Structure
2VNN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Second Generation of Hydroxyethylamine BACE-1 Inhibitors: Optimizing Potency and Oral Bioavailability., Charrier N, Clarke B, Cutler L, Demont E, Dingwall C, Dunsdon R, East P, Hawkins J, Howes C, Hussain I, Jeffrey P, Maile G, Matico R, Mosley J, Naylor A, O'Brien A, Redshaw S, Rowland P, Soleil V, Smith KJ, Sweitzer S, Theobald P, Vesey D, Walter DS, Wayne G, J Med Chem. 2008 May 6;. PMID:18457381
Page seeded by OCA on Sun Jul 27 18:11:48 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Single protein
- Charrier, N.
- Clarke, B.
- Cutler, L.
- Demont, E.
- Dingwall, C.
- Dunsdon, R.
- East, P.
- Hawkins, J.
- Howes, C.
- Hussain, I.
- Jeffrey, P.
- Maile, G.
- Matico, R.
- Mosley, J.
- Naylor, A.
- Obrien, A.
- Redshaw, S.
- Rowland, P.
- Smith, K J.
- Soleil, V.
- Sweitzer, S.
- Theobald, P.
- Vesey, D.
- Walter, D S.
- Wayne, G.
- Alternative splicing
- Asp-2
- Aspartyl protease
- Bace-1
- Beta-secretase
- Beta-site app cleaving enzyme
- Glycoprotein
- Hydrolase
- Memapsin-2
- Membrane
- Protease
- Transmembrane
- Zymogen
