5tln | pdb_00005tln

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Revision as of 17:35, 20 November 2007 by OCA (talk | contribs) (New page: left|200px<br /><applet load="5tln" size="450" color="white" frame="true" align="right" spinBox="true" caption="5tln, resolution 2.3Å" /> '''BINDING OF HYDROXAMIC...)
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File:5tln.gif


5tln, resolution 2.3Å

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BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS

About this Structure

5TLN is a Single protein structure of sequence from Bacillus thermoproteolyticus with CA, ZN and BAN as ligands. Active as Thermolysin, with EC number 3.4.24.27 Full crystallographic information is available from OCA.

Reference

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:7317361

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