3gbp | pdb_00003gbp
STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM
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Overview
The X-ray structure of the periplasmic glucose/galactose receptor (binding, protein) of Salmonella typhimurium has been solved by the method of, multiple isomorphous replacement and refined to a resolution of 2.4 A with, an R-factor of 15.8%. The protein consists of two highly-similar, structural domains with a bound sugar molecule trapped between. A combined, sequence/structural approach is used to compare the structure of this, protein to a similar arabinose receptor. The new sequence alignment, obtained is used to analyze a number of features conserved for structural, and functional reasons. This information allowed the prediction of similar, features within the sequence of the analogous ribose receptor. Some of the, consequences of the structures for chemotaxis and transport are discussed.
About this Structure
3GBP is a Single protein structure of sequence from Salmonella typhimurium with GLC and CA as ligands. This structure superseeds the now removed PDB entry 1GBP. Full crystallographic information is available from OCA.
Reference
Structure of the periplasmic glucose/galactose receptor of Salmonella typhimurium., Mowbray SL, Smith RD, Cole LB, Receptor. 1990-1991 Winter;1(1-2):41-53. PMID:1967096
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