3b2r | pdb_00003b2r
From Proteopedia
Crystal Structure of PDE5A1 catalytic domain in complex with Vardenafil
Template:ABSTRACT PUBMED 17959709
About this Structure
3B2R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Conformational variations of both phosphodiesterase-5 and inhibitors provide the structural basis for the physiological effects of vardenafil and sildenafil., Wang H, Ye M, Robinson H, Francis SH, Ke H, Mol Pharmacol. 2008 Jan;73(1):104-10. Epub 2007 Oct 24. PMID:17959709
Page seeded by OCA on Sun Jul 27 21:53:29 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- 3',5'-cyclic-GMP phosphodiesterase
- Homo sapiens
- Single protein
- Hengming, K.
- Howard, R.
- Huanchen, W.
- Mengchun, Y.
- Sharron, H F.
- Allosteric enzyme
- Alternative splicing
- Cgmp phosphodiesterase
- Cgmp-binding
- Hydrolase
- Levitratm.
- Magnesium
- Metal-binding
- Nucleotide-binding
- Pde5-inhibitor potency
- Phosphorylation
- Polymorphism
- Sildenafil
- Vardenafil
- Zinc