2va6 | pdb_00002va6
From Proteopedia
X-RAY CRYSTAL STRUCTURE OF BETA SECRETASE COMPLEXED WITH COMPOUND 24
About this Structure
2VA6 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency., Edwards PD, Albert JS, Sylvester M, Aharony D, Andisik D, Callaghan O, Campbell JB, Carr RA, Chessari G, Congreve M, Frederickson M, Folmer RH, Geschwindner S, Koether G, Kolmodin K, Krumrine J, Mauger RC, Murray CW, Olsson LL, Patel S, Spear N, Tian G, J Med Chem. 2007 Nov 29;50(24):5912-25. Epub 2007 Nov 7. PMID:17985862
Page seeded by OCA on Mon Jul 28 03:32:13 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Memapsin 2
- Single protein
- Aharony, D.
- Albert, J S.
- Andisik, D.
- Callaghan, O.
- Campbell, J B.
- Carr, R A.
- Chessari, G.
- Congreve, M.
- Edwards, P D.
- Folmer, R H.A.
- Frederickson, M.
- Geschwindner, S.
- Koether, G.
- Kolmodin, K.
- Krumrine, J.
- Mauger, R C.
- Murray, C W.
- Olsson, L.
- Patel, S.
- Spear, N.
- Sylvester, M.
- Tian, G.
- Alternative splicing
- Alzheimer's disease
- Aspartic protease
- Aspartyl protease
- Base
- Beta-secretase
- Glycoprotein
- Hydrolase
- Membrane
- Protease
- Transmembrane
- Zymogen
