3bef | pdb_00003bef
Crystal structure of thrombin bound to the extracellular fragment of PAR1
Template:ABSTRACT PUBMED 18250335
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3BEF is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structural identification of the pathway of long-range communication in an allosteric enzyme., Gandhi PS, Chen Z, Mathews FS, Di Cera E, Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
Molecular dissection of Na+ binding to thrombin., Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E, J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000
Crystal structure of thrombin in a self-inhibited conformation., Pineda AO, Chen ZW, Bah A, Garvey LC, Mathews FS, Di Cera E, J Biol Chem. 2006 Oct 27;281(43):32922-8. Epub 2006 Sep 5. PMID:16954215
Page seeded by OCA on Mon Jul 28 09:33:57 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Homo sapiens
- Protein complex
- Thrombin
- Bah, A.
- Cera, E Di.
- Chen, Z.
- Gandhi, P S.
- Mathews, F S.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- G-protein coupled receptor
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Membrane
- Phosphoprotein
- Polymorphism
- Receptor
- Secreted
- Serine protease
- Transducer
- Transmembrane
- Zymogen
