2g19 | pdb_00002g19

File:2g19.png

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2g19, resolution 1.70Å (default scene)
Ligands:	4HG, FE2
Structural annotation: Resources: InterPro : Ipr002893, Ipr005123, Ipr006620 Pfam : PF03171 UniProt : Q9GZT9
Functional annotation: Cellular component: cytosol Biological process: protein metabolic process Molecular function: protein binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen L-ascorbic acid binding metal ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors iron ion binding zinc ion binding oxidoreductase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

About this Structure

2G19 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)., McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Lienard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ, Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. Epub 2006 Jun 16. PMID:16782814

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