2fir | pdb_00002fir
From Proteopedia
Template:ABSTRACT PUBMED 16757484
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| 2fir, resolution 2.00Å (default scene) | |||||||||||||
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| Ligands: | 0G7, CA, CL, FUC, GLC, MG, NA, ZN | ||||||||||||
| Non-Standard Residues: | CGU | ||||||||||||
| Gene: | F7 (Homo sapiens), F3 (Homo sapiens) | ||||||||||||
| Activity: | Coagulation factor VIIa, with EC number 3.4.21.21 | ||||||||||||
| Related: | 1dan, 2a2q, 2aer, 2b8o | ||||||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of DFPR-VIIa/sTF
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
2FIR is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa., Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K, J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484
Page seeded by OCA on Tue Jul 29 13:27:34 2008
