2r2m | pdb_00002r2m
From Proteopedia
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Template:ABSTRACT PUBMED 17889527
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
2R2M is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527
Page seeded by OCA on Wed Aug 27 11:08:24 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Hirudo medicinalis
- Homo sapiens
- Protein complex
- Thrombin
- Spurlino, J.
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Polymorphism
- Protease
- Protease inhibitor
- Secreted
- Serine protease
- Serine protease inhibitor
- Sulfation
- Zymogen