2rgp | pdb_00002rgp
From Proteopedia
Structure of EGFR in complex with hydrazone, a potent dual inhibitor
About this Structure
2RGP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors., Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA, Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:18653333
Page seeded by OCA on Wed Aug 27 11:09:10 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
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- Homo sapiens
- Receptor protein-tyrosine kinase
- Single protein
- Abad, M C.
- Alternative splicing
- Anti-oncogene
- Atp-binding
- Cell cycle
- Disease mutation
- Glycoprotein
- Kinase domain
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Receptor
- Secreted
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Ubl conjugation