1s7o | pdb_00001s7o
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Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes
Overview
The crystal structure of the putative DNA-binding protein SP_1288, (gi/15675166, also listed as gi/28895954) from Streptococcus pyogenes has, been determined by X-ray crystallography to a resolution of 2.3 A using, anomalous diffraction data at the Se peak wavelength. SP_1288 belongs to a, family of proteins whose cellular function is associated with the signal, recognition particle; no structural information has been available until, now about the members of the family. Crystallographic analysis revealed, that the overall fold of SP_1288 consists exclusively of alpha-helices and, that 75% of the structure has good similarity to domain 4 of the sigma, subunit of RNA polymerase. This suggests its possible involvement in the, biochemical function of transcription initiation, which includes, interaction with DNA.
About this Structure
1S7O is a Single protein structure of sequence from Streptococcus pyogenes. Full crystallographic information is available from OCA.
Reference
Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes., Oganesyan V, Pufan R, DeGiovanni A, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1266-71. Epub 2004, Jun 22. PMID:15213388
Page seeded by OCA on Wed Nov 21 02:10:28 2007
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Single protein
- Streptococcus pyogenes
- BSGC, Berkeley.Structural.Genomics.Center.
- DeGiovanni, A.
- Kim, R.
- Kim, S.H.
- Oganesyan, V.
- Pufan, R.
- Yokota, H.
- Berkeley structural genomics center
- Bsgc
- Protein structure initiative
- Psi
- Putative dna binding protein; structural genomics
- Rna polymerase sigma factor
- Signal recognition particle
- Structure funded by nih
- Upf0122
- X-rat crystallography
