3efk | pdb_00003efk
Structure of c-Met with pyrimidone inhibitor 50
Template:ABSTRACT PUBMED 18763753
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
3EFK is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Design, synthesis, and biological evaluation of potent c-Met inhibitors., D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS, J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:18763753
Page seeded by OCA on Wed Oct 8 09:36:24 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Single protein
- Angelo, N D.
- Bellon, S F.
- Dussault, I.
- Whittington, D.
- Alternative splicing
- Atp-binding
- C-met
- Chromosomal rearrangement
- Disease mutation
- Glycoprotein
- Kinase
- Kinase inhibitor pyrimidone
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Proto-oncogene
- Receptor
- Transferase
- Transmembrane
- Tyrosine-protein kinase
