3e8r | pdb_00003e8r
From Proteopedia
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
Template:ABSTRACT PUBMED 18835710
About this Structure
3E8R is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: Optimization of the S3' pocket., Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X, Bioorg Med Chem Lett. 2008 Sep 13. PMID:18835710
Page seeded by OCA on Wed Oct 22 10:51:38 2008
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Categories:
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- ADAM 17 endopeptidase
- Homo sapiens
- Single protein
- Orth, P.
- Alternative splicing
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Protease
- Sh3-binding
- Tace adam17 zn-endopeptidase
- Transmembrane
- Zinc
- Zymogen