2vx1 | pdb_00002vx1
EPHB4 KINASE DOMAIN INHIBITOR COMPLEX
About this Structure
2VX1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Inhibitors of the tyrosine kinase EphB4. Part 2: Structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines., Bardelle C, Coleman T, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ, Bioorg Med Chem Lett. 2008 Sep 27. PMID:18851911
Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines., Bardelle C, Cross D, Davenport S, Kettle JG, Ko EJ, Leach AG, Mortlock A, Read J, Roberts NJ, Robins P, Williams EJ, Bioorg Med Chem Lett. 2008 May 1;18(9):2776-80. Epub 2008 Apr 10. PMID:18434142
Page seeded by OCA on Wed Oct 29 10:50:24 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Single protein
- Barratt, D.
- Brassington, C A.
- Green, I.
- Kettle, J G.
- Leach, A G.
- Mccall, E J.
- Read, J.
- Valentine, A L.
- Atp-binding
- Glycoprotein
- Kinase
- Membrane
- Mutant
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Receptor
- Receptor tyrosine kinase
- Transferase
- Transmembrane
- Tyrosine-protein kinase
- Unphosphorylated
