3e6p | pdb_00003e6p
Crystal structure of human meizothrombin desF1
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
3E6P is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Na(+) binding to meizothrombin desF1., Papaconstantinou ME, Gandhi PS, Chen Z, Bah A, Di Cera E, Cell Mol Life Sci. 2008 Nov;65(22):3688-97. PMID:18854941
New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK., Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF, Structure. 1997 Dec 15;5(12):1681-93. PMID:9438869
Page seeded by OCA on Thu Nov 20 07:45:00 2008
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- Homo sapiens
- Thrombin
- Bah, A.
- Cera, E Di.
- Chen, Z.
- Gandhi, P.
- Papaconstantinou, M E.
- Acute phase
- Allostery
- Blood coagulation
- Calcium
- Cleavage on pair of basic residue
- Disease mutation
- Gamma-carboxyglutamic acid
- Glycoprotein
- Hydrolase
- Kringle
- Linkage
- Meizothrombin
- Na+ binding
- Pharmaceutical
- Polymorphism
- Protease
- Secreted
- Serine protease
- Zymogen