3ens | pdb_00003ens
From Proteopedia
Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
Template:ABSTRACT PUBMED 18998662
About this Structure
3ENS is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors., Shi Y, Sitkoff D, Zhang J, Klei HE, Kish K, Liu EC, Hartl KS, Seiler SM, Chang M, Huang C, Youssef S, Steinbacher TE, Schumacher WA, Grazier N, Pudzianowski A, Apedo A, Discenza L, Yanchunas J Jr, Stein PD, Atwal KS, J Med Chem. 2008 Nov 11. PMID:18998662
Page seeded by OCA on Wed Dec 31 10:33:40 2008
