3f66 | pdb_00003f66
From Proteopedia
Human c-Met Kinase in complex with quinoxaline inhibitor
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
3F66 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase., Porter J, Lumb S, Lecomte F, Reuberson J, Foley A, Calmiano M, le Riche K, Edwards H, Delgado J, Franklin RJ, Gascon-Simorte JM, Maloney A, Meier C, Batchelor M, Bioorg Med Chem Lett. 2008 Nov 21. PMID:19059779
Page seeded by OCA on Wed Jan 7 08:17:51 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Ceska, T.
- Meier, C.
- Alternative splicing
- Atp-binding
- C-met
- Chromosomal rearrangement
- Disease mutation
- Glycoprotein
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Protein kinase
- Proto-oncogene
- Quinoxaline
- Receptor
- Repeat
- Signal
- Transferase
- Transmembrane
- Tyrosine-protein kinase.
