3fcu | pdb_00003fcu
From Proteopedia
Structure of headpiece of integrin aIIBb3 in open conformation
Template:ABSTRACT PUBMED 19111664
Disease
Known disease associated with this structure: Glanzmann thrombasthenia, type A OMIM:[607759], Thrombocytopenia, neonatal alloimmune OMIM:[607759]
About this Structure
3FCU is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhu J, Luo BH, Xiao T, Zhang C, Nishida N, Springer TA. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol Cell. 2008 Dec 26;32(6):849-61. PMID:19111664 doi:10.1016/j.molcel.2008.11.018
Page seeded by OCA on Wed Jan 21 10:49:26 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Luo, B H.
- Nishida, N.
- Springer, T A.
- Xiao, T.
- Zhang, C.
- Zhu, J.
- Allostery
- Alternative splicing
- Cell adhesion
- Cell adhesion/blood clotting complex
- Cell adhesion/immune system complex
- Crystal structure
- Disease mutation
- Fibrinogen binding
- Glycoprotein
- Host-virus interaction
- Integrin
- Membrane
- Phosphoprotein
- Platelet integrin alphaiibbeta3
- Polymorphism
- Receptor
- Therapeutic antagonism
- Transmembrane
