2w1d | pdb_00002w1d
From Proteopedia
STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR
About this Structure
2W1D is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Howard S, Berdini V, Boulstridge JA, Carr MG, Cross DM, Curry J, Devine LA, Early TR, Fazal L, Gill AL, Heathcote M, Maman S, Matthews JE, McMenamin RL, Navarro EF, O'Brien MA, O'Reilly M, Rees DC, Reule M, Tisi D, Williams G, Vinkovic M, Wyatt PG. Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity. J Med Chem. 2009 Jan 22;52(2):379-88. PMID:19143567 doi:10.1021/jm800984v
Page seeded by OCA on Wed Jan 28 09:37:15 2009
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Categories:
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- Homo sapiens
- Non-specific serine/threonine protein kinase
- Berdini, V.
- Boulstridge, J A.
- Brien, M A.O.
- Carr, M G.
- Cross, D M.
- Curry, J.
- Devine, L A.
- Early, T R.
- Fazal, L.
- Gill, A L.
- Heathcote, M.
- Howard, S.
- Maman, S.
- Matthews, J E.
- Mcmenamin, R L.
- Navarro, E F.
- Rees, D C.
- Reilly, M O.
- Reule, M.
- Tisi, D.
- Vinkovic, M.
- Williams, G.
- Wyatt, P G.
- Atp-binding
- Aurora
- Cancer
- Cell cycle
- Inhibitor
- Kinase
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Serine/threonine-protein kinase
- Transferase