2hd1 | pdb_00002hd1

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File:2hd1.png

Template:STRUCTURE 2hd1

Crystal structure of PDE9 in complex with IBMX

Template:ABSTRACT PUBMED 15210993

Disease

Known disease associated with this structure: Epilepsy, pyridoxine-dependent OMIM:[107323]

About this Structure

2HD1 is a 2 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 1tbm. Full crystallographic information is available from OCA.

Reference

  1. Huai Q, Wang H, Zhang W, Colman RW, Robinson H, Ke H. Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9624-9. Epub 2004 Jun 21. PMID:15210993 doi:10.1073/pnas.0401120101

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