2b8l | pdb_00002b8l

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Template:STRUCTURE 2b8l

File:2b8l.png

Crystal structure of human beta secretase complexed with inhibitor

Template:ABSTRACT PUBMED 16263281

About this Structure

2B8L is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Stachel SJ, Coburn CA, Steele TG, Crouthamel MC, Pietrak BL, Lai MT, Holloway MK, Munshi SK, Graham SL, Vacca JP. Conformationally biased P3 amide replacements of beta-secretase inhibitors. Bioorg Med Chem Lett. 2006 Feb;16(3):641-4. Epub 2005 Nov 2. PMID:16263281 doi:10.1016/j.bmcl.2005.10.032

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