3bes | pdb_00003bes

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File:3bes.png

Template:STRUCTURE 3bes

Structure of a Poxvirus ifngbp/ifng Complex

Template:ABSTRACT PUBMED 18252829

Disease

Known disease associated with this structure: AIDS, rapid progression to OMIM:[147570], Aplastic anemia OMIM:[147570], Hepatitis C virus, resistance to OMIM:[147570], TSC2 angiomyolipomas, renal, modifier of OMIM:[147570], Tuberculosis, protection against OMIM:[147570]

About this Structure

3BES is a 2 chains structure of sequences from Ectromelia virus and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Nuara AA, Walter LJ, Logsdon NJ, Yoon SI, Jones BC, Schriewer JM, Buller RM, Walter MR. Structure and mechanism of IFN-gamma antagonism by an orthopoxvirus IFN-gamma-binding protein. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1861-6. Epub 2008 Feb 5. PMID:18252829

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