2nqi | pdb_00002nqi

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File:2nqi.png

Template:STRUCTURE 2nqi

Calpain 1 proteolytic core inactivated by WR13(R,R), an epoxysuccinyl-type inhibitor.

Template:ABSTRACT PUBMED 17218315

About this Structure

2NQI is a 1 chain structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Cuerrier D, Moldoveanu T, Campbell RL, Kelly J, Yoruk B, Verhelst SH, Greenbaum D, Bogyo M, Davies PL. Development of calpain-specific inactivators by screening of positional scanning epoxide libraries. J Biol Chem. 2007 Mar 30;282(13):9600-11. Epub 2007 Jan 11. PMID:17218315 doi:10.1074/jbc.M610372200

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