2vny | pdb_00002vny

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File:2vny.png

Template:STRUCTURE 2vny

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH (1-(9H-PURIN-6-YL)PIPERIDIN-4-YL)AMINE

Template:ABSTRACT PUBMED 18345609

About this Structure

2VNY is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Caldwell JJ, Davies TG, Donald A, McHardy T, Rowlands MG, Aherne GW, Hunter LK, Taylor K, Ruddle R, Raynaud FI, Verdonk M, Workman P, Garrett MD, Collins I. Identification of 4-(4-Aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as Selective Inhibitors of Protein Kinase B through Fragment Elaboration. J Med Chem. 2008 Apr 10;51(7):2147-57. Epub 2008 Mar 18. PMID:18345609 doi:10.1021/jm701437d

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