2ghm | pdb_00002ghm

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File:2ghm.png

Template:STRUCTURE 2ghm

Mutated MAP kinase P38 (Mus Musculus) in complex with Inhbitor PG-895449

Template:ABSTRACT PUBMED 16632356

About this Structure

2GHM is a 1 chain structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ. Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. Epub 2006 May 2. PMID:16632356 doi:10.1016/j.bmcl.2006.03.095

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