2ow3 | pdb_00002ow3

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Template:STRUCTURE 2ow3

File:2ow3.png

Glycogen synthase kinase-3 beta in complex with bis-(indole)maleimide pyridinophane inhibitor

Template:ABSTRACT PUBMED 17350261

About this Structure

2OW3 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Zhang HC, Bonaga LV, Ye H, Derian CK, Damiano BP, Maryanoff BE. Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3. Bioorg Med Chem Lett. 2007 May 15;17(10):2863-8. Epub 2007 Feb 25. PMID:17350261 doi:10.1016/j.bmcl.2007.02.059

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