2fy2 | pdb_00002fy2

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File:2fy2.png

Template:STRUCTURE 2fy2

Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis

Template:ABSTRACT PUBMED 17144655

Disease

Known disease associated with this structure: Myasthenic syndrome, congenital, associated with episodic apnea OMIM:[118490]

About this Structure

2FY2 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kim AR, Rylett RJ, Shilton BH. Substrate binding and catalytic mechanism of human choline acetyltransferase. Biochemistry. 2006 Dec 12;45(49):14621-31. PMID:17144655 doi:10.1021/bi061536l

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