2brn | pdb_00002brn
From Proteopedia
STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY
Template:ABSTRACT PUBMED 15974586
About this Structure
2BRN is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Foloppe N, Fisher LM, Howes R, Kierstan P, Potter A, Robertson AG, Surgenor AE. Structure-based design of novel Chk1 inhibitors: insights into hydrogen bonding and protein-ligand affinity. J Med Chem. 2005 Jun 30;48(13):4332-45. PMID:15974586 doi:10.1021/jm049022c
Page seeded by OCA on Mon Feb 16 13:47:31 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Fisher, L M.
- Foloppe, N.
- Howes, R.
- Kierstan, P.
- Potter, A.
- Robertson, A G.S.
- Surgenor, A E.
- Atp-binding
- Cell cycle
- Dna damage
- Drug design
- Furanopyrimidine
- Kinase
- Molecular recognition
- Nuclear protein
- Oncology
- Phosphorylation
- Polymorphism
- Pyrrolopyrimidine
- Serine/threonine-protein kinase
- Transferase
