2uw0 | pdb_00002uw0

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File:2uw0.png

Template:STRUCTURE 2uw0

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 6-(4-(4-(4-CHLORO-PHENYL)-PIPERIDIN-4-YL)-PHENYL)-9H-PURINE

Template:ABSTRACT PUBMED 17451235

About this Structure

2UW0 is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Donald A, McHardy T, Rowlands MG, Hunter LJ, Davies TG, Berdini V, Boyle RG, Aherne GW, Garrett MD, Collins I. Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design. J Med Chem. 2007 May 17;50(10):2289-92. Epub 2007 Apr 24. PMID:17451235 doi:10.1021/jm0700924

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