3e8r | pdb_00003e8r

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File:3e8r.png

Template:STRUCTURE 3e8r

Crystal structure of catalytic domain of TACE with hydroxamate inhibitor

Template:ABSTRACT PUBMED 18835710

About this Structure

3E8R is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X. Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5809-14. Epub 2008 Sep 13. PMID:18835710 doi:10.1016/j.bmcl.2008.09.045

Page seeded by OCA on Mon Feb 16 14:42:07 2009

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OCA

[1] Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X. Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5809-14. Epub 2008 Sep 13. PMID:18835710 doi:10.1016/j.bmcl.2008.09.045

3e8r | pdb_00003e8r

Crystal structure of catalytic domain of TACE with hydroxamate inhibitor

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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