1mwp | pdb_00001mwp

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1mwp.png

1mwp, resolution 1.80Å (default scene)

Structural annotation:
Resources:	CATH : 1Mwpa00 InterPro : Ipr011178, Ipr008155, Ipr008154, Ipr015849, Ipr002223, Ipr013803 Pfam : PF02177 SCOP : d1mwpa_ UniProt : P05067

Functional annotation:
Cellular component:	extracellular region membrane integral to membrane integral to plasma membrane cell surface coated pit
Biological process:	endocytosis apoptosis cellular copper ion homeostasis cell adhesion Notch signaling pathway neuromuscular process
Molecular function:	heparin binding endopeptidase inhibitor activity zinc ion binding protein binding copper ion binding metal ion binding identical protein binding iron ion binding serine-type endopeptidase inhibitor activity binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN

Template:ABSTRACT PUBMED 10201399

About this Structure

1MWP is a 1 chain structure of sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full crystallographic information is available from OCA.

Reference

Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat Struct Biol. 1999 Apr;6(4):327-31. PMID:10201399 doi:10.1038/7562

Page seeded by OCA on Mon Feb 16 14:49:07 2009

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OCA

[1] Rossjohn J, Cappai R, Feil SC, Henry A, McKinstry WJ, Galatis D, Hesse L, Multhaup G, Beyreuther K, Masters CL, Parker MW. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat Struct Biol. 1999 Apr;6(4):327-31. PMID:10201399 doi:10.1038/7562

1mwp | pdb_00001mwp

N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEIN

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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