2gs0 | pdb_00002gs0
From Proteopedia
NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and the activation domain of p53
Disease
Known disease associated with this structure: Adrenal cortical carcinoma OMIM:[191170], Breast cancer OMIM:[191170], Choroid plexus papilloma OMIM:[191170], Colorectal cancer OMIM:[191170], Hepatocellular carcinoma OMIM:[191170], Li-Fraumeni syndrome OMIM:[191170], Li-Fraumeni-like syndrome OMIM:[191170], Nasopharyngeal carcinoma OMIM:[191170], Osteosarcoma OMIM:[191170], Pancreatic cancer OMIM:[191170]
About this Structure
2GS0 is a 2 chains structure of sequences from Homo sapiens and Saccharomyces cerevisiae. Full experimental information is available from OCA.
Reference
- Di Lello P, Jenkins LM, Jones TN, Nguyen BD, Hara T, Yamaguchi H, Dikeakos JD, Appella E, Legault P, Omichinski JG. Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol Cell. 2006 Jun 23;22(6):731-40. PMID:16793543 doi:https://dx.doi.org/10.1016/j.molcel.2006.05.007
Page seeded by OCA on Mon Feb 16 14:51:10 2009
