1ook | pdb_00001ook

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Template:STRUCTURE 1ook

File:1ook.png

Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin

Template:ABSTRACT PUBMED 12855810

Disease

Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[606672], Bernard-Soulier syndrome, type A OMIM:[606672], von Willebrand disease, platelet-type OMIM:[606672], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[606672]

About this Structure

1OOK is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Celikel R, McClintock RA, Roberts JR, Mendolicchio GL, Ware J, Varughese KI, Ruggeri ZM. Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha. Science. 2003 Jul 11;301(5630):218-21. PMID:12855810 doi:https://dx.doi.org/10.1126/science.1084183

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